Network as biomarker
نویسندگان
چکیده
منابع مشابه
Metabolic network as a progression biomarker of premanifest Huntington's disease.
BACKGROUND The evaluation of effective disease-modifying therapies for neurodegenerative disorders relies on objective and accurate measures of progression in at-risk individuals. Here we used a computational approach to identify a functional brain network associated with the progression of preclinical Huntington's disease (HD). METHODS Twelve premanifest HD mutation carriers were scanned wit...
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Objective: Multiple sclerosis (MS) is presented with motor and sensory function loss. It is caused by demyelination and following axonal lesion. As myelin basic protein (MBP) is one of the key elements of the myelin cover, we examined the level of MBP in serum, stimulated, and unstimulated saliva as a suitable biomarker for detecting MS. Methods: A case-control study was performed in 29 health...
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Introduction: MicroRNAs are small, non-coding, and protected RNA molecules that regulate gene expression after transcription by mRNA degradation or inhibition of protein synthesis. The function of these molecules is critical to many cellular processes, including growth, development, differentiation, homeostasis, apoptosis, aging, stress resistance. In addition, some diseases including cancer, a...
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ژورنال
عنوان ژورنال: Systems Biomedicine
سال: 2013
ISSN: 2162-8130,2162-8149
DOI: 10.4161/sysb.26474